Webb9 dec. 2024 · When comparing the clinical benefit of blocking IL-31 in horses with other species, we noticed a reduction of skin lesion severity in IBH-affected horses, which is in contrast to atopic dermatitis trials in dogs and humans that only showed reduction of pruritus whereas no improvement of eczema. 37, 42 This suggests a meaningful impact … Webb30 sep. 2014 · In P1, a significant association between RAO and IBH phenotypes was found, but not between RAO and URT or IBH and URT. In RAO+ horses, 3 of 11 (27%) suffered from IBH in contrast to 3 of 108 (3%) of RAO− horses (P = .01; Fig 1). No associations between RAO, IBH, URT, and environmental and management factors …

Equine Insect Bite Hypersensitivity (IBH)

Webb1192 Icelandic horses born in Germany, where Culicoides are endemic, suffered from summer eczema. If both parents had IBH, prevalence increased to 12.2% and, in contrast, if only one parent had IBH, it decreased to 6.5%. However, if neither one of the parents was affected, prevalence was at 2.9%. Heritability with an incidence of 8.8% hemco 13130

Component-resolved microarray analysis of IgE sensitization …

WebbHere, we investigate the role of IL-31 in IBH of horses and developed a therapeutic vaccine against equine IL-31 (eIL-31). Methods: IL-31 levels were quantified in allergen … Webb18 sep. 2024 · Horses affected with insect bite hypersensitivity (IBH) show airway hyperreactivity (AH) to inhaled histamine, even in the absence of overt clinical signs of equine asthma (EA). Animals Twenty-two healthy controls (group C), 24 horses suffering from IBH alone (group IBH), and 23 horses suffering from IBH and EA (group IBH/EA). … WebbIceland were included in the study. These horses had been used in a previous study [20]. Data and sera from 92 horses living in Sweden (55 with IBH and 37 healthy controls) was also utilized [20, 21]. In 27 of the 55 Swedish IBH horses the duration of disease at time of blood sampling was known, and as such were grouped according to disease ... hemco blower