WebApr 14, 2024 · D, KTB103 TONSL-overexpressing cells are predominantly luminal progenitors based on CD49f and EpCAM staining pattern (CD49f + /EpCAM +). Primary KTB103 cells contained luminal progenitor and basal/stem cell subpopulation. E, Only HRas G12V plus SV40-T/t antigen–overexpressing cells generated tumors in NSG mice. … WebMay 21, 2024 · CD49f defines bladder tumor cells with multiple lineage signatures scRNA-seq analysis identified populations of mouse and human epithelia with high expression of basal, luminal, and...
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WebNational Center for Biotechnology Information WebFor instance, in breast cancer, the CD24 −/lo /epithelial cell adhesion molecule (EpCAM) lo CSC phenotype resembles that of CD49f + /ESA −/lo normal human mammary stem cell 11,12 and aldehyde dehydrogenase 1 (ALDH1), a marker of normal mammary stem cells, is a well-established breast cancer stem cell (BCSC) marker. 13 It is proposed that ... how turmeric is good for health
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WebAug 2, 2009 · The CD49f − EpCAM + subpopulation expressed only luminal lineage markers including estrogen receptor and progesterone receptor, whereas the fourth subpopulation (CD49f − EpCAM −) was called ... WebSep 2, 2010 · As expected on the basis of our previous genomic analysis of the differentiation status of these cell lines, virtually all claudin-low SUM159PT cells showed a stromal or MaSC antigenic phenotype (CD49f + /EpCAM-), ~98% of MCF-7 cells showed a mL phenotype (CD49f-/low /EpCAM +), and ~83% of SUM149PT cells showed a pL … WebSep 15, 2013 · The anthrax toxin receptor 1 (ANTXR1) has been identified as a functional biomarker of normal stem cells and breast cancer stem-like cells. Primary stem cell-enriched basal cells (CD49f (+)/EpCAM (-)/Lin (-)) expressed higher levels of ANTXR1 compared with mature luminal cells. how turmeric grows